How to Stack Nootropics

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Introduction to How to Stack Nootropics

You’ve seen them or you’ve taken pre-made commercial nootropic stacks or maybe you’ve been thinking of making your own stack, but how and what exactly is stacking? Making your own nootropic stack is popular, but you need to know how to stack nootropics first.How to stack nootropics

What is nootropic stacking? Simply put, it is the process of combining two or more nootropic supplements together for a better effect. This is much different than taking a higher dose of one nootropic for a better effect.

What you are hoping to achieve is perhaps a combination of mood enhancer, increase your energy, be more focused, etc. It’s all possible.

Custom or Pre-formulated Stack

Which do you want to do? Make your own or buy pre-formulated. Stacking your own takes a lot of research and understanding before you can even think about making your own. It’s not easy and can be dangerous and pose some real health risks to you.

Pre-Formulated Stack

Before you dive into this, it is very important that you fully understand each nootropic drug your wish to combine and what you may expect, good or bad. Just grabbing two or three nootropic supplements and combining them could be full of disastrous side effects.

The first option I would suggest is a pre-formulated commercial stack.  Something like Qualia Mind. Some offer overall cognitive enhancements and some are geared specifically to say motivation or focus. This way you can get an idea of what it is you want without worrying about making your own. You can also learn along the way.

Buying them pre-formulated you know that there is at least some (depending on the manufacturer) lab testing before they get to the store.

Your Own Stack

Undoubtedly creating your own stack gives you the most options to be creative. You can also change the dosages as you see fit. Keep in mind this needs knowledge and research.

You can also consider true cost. Pre-formulated commercial stacks can set you back quite a bit of money and keep buying them over and over may not be economical for you.


Where to start With Custom

Before you start, You need to ask yourself a few questions:

What effect do I want with this stack? Have I educated myself enough? How much will it cost? When and how often am I willing to take this stack? Is this a stack I need to take over time to get effects from? What are the side effects if any? Is it safe?

The most important part in creating your own stack after you decide what you want out of it is research. Supplements whether natural or synthetic can be dangerous. There are a number of combinations that cannot be combined and this needs to be understood.
There are websites available to you that have example stacks they have tried and are proven to be safe and to work well at what they are created to do. These are great stacks to experiment with and learn how and why these nootropics go together.

Another important part of researching is looking at studies and experience reports by other nootropic users )Please take what you read on Reddit with a grain of salt). This is the best way to find out if something is likely to be effective or not.

If you do your research, come up with your own stack that works and is safe, then creating you may be the way to go.

What is Synergy?

Earlier I said you just can’t stack random nootropic supplements. You need to know which will bond synergistically with the other. Simply put, synergy means that you want the two drugs to enhance or increase the effects together. You also want no harsh side effects from combining the two.

The best example of two nootropics working together is caffeine and L-Theanine. These two are found in green tea all Synergy

over the world and offer a great effect together. The L-theanine produces a calm, relaxed, zen feeling without drowsiness. The Caffeine gives us the alertness and energy boost but has very annoying side effects we all know; shaky hands, the jitters, and the crash soon after.

Putting the two together just works. The L-theanine counteracts the sided effects of the caffeine. What you get then is all the effects of L-theanine, all the effects of caffeine, but no caffeine side effects. It’s a beautiful and simple stack.

If you are going to start your own nootropic stack, you need to keep this synergy concept at the forefront and there is only one responsible way to test this. That is low doses. By starting with low doses you learn how you are being effected without taking risks. Up the doses until you achieve the desired effect with no nasty side effects.

What to do About Side Effects

There are a number of nootropics that are very potent and have to be handled with care so to speak. Nootropics are mostly sold as supplements and therefore you see doses as suggested and not prescribed as prescription medications are. Take too much of your prescription medication and risk a serious overdose that could actually kill you.

Take too much of a supplement and you are just upping the dosage from what is suggested. Now you leave yourself wide open to overdosing typically called side effects from high doses in the nootropic world. We don’t read too much about people overdosing on nootropics, but it happens more often than we think.

There are other milder negative effects that new nootropic users are likely to experience. These are vastly different than the ‘side effects’ from high dosages. They typically are things like a headache, dizziness, and nausea. These usually disappear after a couple of days.

More on Keeping it Low

It is always the way. You are new and you want something great so you go big. Go big or go home is something we have all heard and joked about, but in the world of nootropics it is simply wrong and you can put health at risk.

New users should always start their doses lower than what is on the label and slowly work up to the suggested dose and stack that way. This way you can adjust slowly to the effects you have on your brain.

If you want to go big when talking about the number of nootropics you want to stack together, you need to be careful here as well because the dosages need to be right and with minimal to no side effects.

Your Safety

Many nootropics are natural and many are synthetic. Either way, they all have safety issues. There are studies done on most of the nootropics out there yet there still is no regulation and most medical professionals are ready to debunk them at the first chance they get.

This leads to people treating them like candy and getting themselves into serious trouble when stacking. It’s totally unnecessary. These substances are safe when you know how to stack properly.

Pill popping is another problem especially in colleges or universities where students are studying for long periods of time. Take a pill and an hour later take another and repeat this for hours on end while completely ignoring the proper dosage written on the label.

Another problem is the stackers who think they know supplements and stack without knowledge of what they are stacking. There is no understanding that these are drugs, but emergency department doctors and nurses understand because they are quite experienced in supplement overdoses.


Simple Sample Stacks

Caffeine + L-Theanine Nootropic Stack

This is possibly the safest stack around. It occurs naturally in green tea and is consumed just about everywhere in the world.

If you want to create your own and not in tea, combine them in a 2:1 ratio of L-theanine to Caffeine. This way you get a Caffeine and l-theanine

boost in your mental energy from the coffee and a calm but effective focus from the L-theanine.


200mg L-theanine 100mg Caffeine

St. John’s Wart + Ashwagandha

Those suffering from social anxiety are often suffering from depression as a result of their social anxiety. Not being able to go out and talk to people makes people depressed. On the other hand, people who suffer from depression often don’t want to go out, talk to people or socialize in any way, a kind of social anxiety.

Combining St. John’s Wart and Ashwagandha can help to reduce the feelings of both your depression and your social anxiety.

St. John’s Wart causes your body to create more serotonin and thus makes you feel better.

Ashwagandha works as a depressant on your central nervous system. By relaxing your nervous system, you are able to think more clearly without the anxiety.


StJohn’s Wort 900mg to 1,800mg. Ashwagandha, 450mg and up to 500mg and up in a capsule. This should always be in combination with St. John’s Wort

To Wrap it Up

Now that you have a better understanding of stacking, there are a few extra things to keep in mind. First, we are all different and certain nootropics will work well for some and not so well for others. If one stack you try isn’t doing it for you, make a change.Stacking

You can change the dosage a little or even change the number of times a day you take it. Don’t give up and don’t change all the time. You need to try one for a while, get a feel for it and then when you know this, you can make changes.

Research is the most important part of making your stack. Read, learn, ask. Do what you need to do to know everything about what you want to do before you do it.

Now that you’ve read this, I have an article called I have an article called Nootropic Stacks for Beginners

10 thoughts on “How to Stack Nootropics”

  1. Before reading this article today I had no idea what Nootropics exactly was. But this article explained very well about Nootropics and also about stacking them for a better effect. And also the explanations were really simple and easy to understand. I also learned about the dosages which is great.

    Thank you so much for sharing this article.

  2. Thanks for the sample stacks! Do you happen to have a list of the top 10 or the top 15 most common “safe” stacks out there?

    I’m a newbie when it comes to stacking, but I’m always looking to tweak and try new things to see what kind of impact it might have on how I feel and how productive I am throughout the day.

    A few more of the most common stacks would be really helpful for me to give it a try!

  3. Do you have any suggestions for someone struggling with ADHD?  Have you heard of anyone self medication with nootropics?  I don’t have health insurance and I’m looking for other alternatives to treating my ADHD.  Reading your article gives me hope that maybe there is the right “stack” I can use to help me focus.  What do you think?  Can nootropics help with this issue?

  4. Your post about How to Stack Nootropics was very catchy. I’d never thought about combinating suplements.

    The example of the combination of Caffein and L-theanine was very good. I am a huge coffee fan. I will try this combo. I will also read some of your reviews, because I really want to know more about nootropics.

    • Thanks for the great comment.  Yes, caffeine and L-theanine is one of the most popular stacks yet it is so simple.

      I will be continuing with reviews to add to what is already here. 

  5. Wow! I had no idea this was such a big thing to do, or that it could be such a hazard when done incorrectly! I would think that it would always be best when first starting out that you want to at the very least research pre-done stacks so you can get a feel for what is safe and what isn’t. before that, I would definitely talk to your doctor about doing anything like this. 

    Thank you for all the information though. This has really opened my eyes to what you can do when one is properly educated on how to do things safely.

    • My advice is always to buy a pre-formulated stack first and do that a few times until you are familiar with what it does to you and what it is that is doing what you want.  You can learn a lot from a commercial stack.

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