- 1 Introduction to this Huperzine A Review
- 2 Here’s What Huperzine A Can Do For You
- 3 Side Effects
- 4 Dosage
- 5 My Conclusion
- 6 Where to Buy Huperzine A
Introduction to this Huperzine A Review
This Huperzine A review will show just how important this nootropic is to our brain health. Huperzine A is a natural plant-based neuroprotector found in may herbs that are known to have enhanced memory and learning properties. It is mostly extracted from the Chinese club moss called Huperzia Serrata. Huperzine A has been used in Chinese herbal medicine for a long time even many centuries.
Huperzine A is very useful because of its ability to inhibit an enzyme in our brains that breaks down an important chemical known as Acetylcholine. Acetylcholine is very important for our memories and our learning ability.
While Huperzine A is closely associated with Alzheimer’s and other forms of dementia as well as depression, Huperzine A can be used by people who are ‘brain healthy’. It is a potent memory enhancement supplement and can help you think more clearly.
Huperzine A is used by University students worldwide as a supplement to boost their cognitive abilities and is one of my choices for best nootropics for focus. You can also find it as one of my top 10 natural nootropics.
Here’s What Huperzine A Can Do For You
It’s a Memory Enhancer:
Huperzine A increases your levels of acetylcholine, therefore, improving your memory. Studies show that it significantly inhibits acetylcholinesterase production. Acetylcholinesterase is an enzyme which breaks down acetylcholine. By inhibiting this enzyme Huperzine A plays a big part in raising the levels of acetylcholine in our brains and of course, that enhances our cognition and our memory.
Enhance Memory & Learning of Adolescent Students
In a fairly small, double-blind, placebo-controlled study, 34 pairs of middle & junior school aged adolescents who complained about memory were chosen to receive administration of either 100 mcg Huperzine A or placebo daily for a 4-week period. By the end of the study, the researchers found the Huperzine A group scored better on the Memory Quotient tests than the placebo group, leading to the conclusion that this nootropic supplement enhances the memory and learning performance of adolescent students namely on language. 
May Help Maintain Healthy Brain Function
Huoperzine A also has the benefit of being able to maintain healthy brain function. A number of animal studies have shown us that it is very good at protecting neurons.
Relieves or Lowers Symptoms of Depression
Huperzine A is used for many purposes, and, among them, it is used as a natural antidepressant. Unlike other antidepressants, Huperzine A does not act directly against depression, but it helps our brain function normal, which is an important aspect of combating depression.
Another review done in 2016 of three clinical trials are telling us Huperzine A may have the benefit of alleviating cognitive impairment symptoms of major depressive disorders. . In these trials, they used 238 participants ranging in age from 16 up to 60. The trials compared the effectiveness of treating depression with Huperzine A. The treatment didn’t work for depression, however, it did significantly improve the cognitive functioning and quality of life.
How does Huperzine A work for depression
Depression is caused by a whole host of different external or internal factors. Looking at it from the physiological side, the lack of or insufficient amount of some neurotransmitters in our brains can play a large part in causing depression. Given that, Huperzine A as I mentioned above prevents the breakdown of acetylcholine in our brains effectively preserving brain health.
Huperzine isn’t an antidepressant nor does it act as an antidepressant, but Huperzine A helps alleviate the symptoms of depression by way of it keeping up our brain’s health.
For example, a 2016 review of three clinical trials suggests that Huperzine A may be effective in alleviating the cognitive impairment symptoms of major depressive disorders. A total of 238 people aged 16 to 60 were involved in the trials, which compared the effectiveness of antidepressant treatment to treatment with antidepressant supplemented with huperzine A. While the addition of huperzine A did not appear to treat the depressive disorders, the group who took both antidepressants and huperzine A showed significantly greater improvement in both cognitive functioning and quality of life.
Glutamate Toxicity Protection
What is Glutamine toxicity? First, Glutamate is a powerful neurotransmitter which sends signals between nerve cells. If present in normal levels Glutamine plays a very important role in learning and memory. When levels are too high it may become toxic to our brains and lead to cellular death. Chronic glutamate toxicity caused by oversensitive receptors is associated with neurodegenerative diseases and causes anxiety, restlessness, increased sensitivity to pain, and a diminished ability to focus or concentrate.
Huperzine A has been shown to act as an antagonist to glutamate receptors in the brain, preventing neurons from being over activated by glutamate. This action helps normalize glutamate levels.
Reduces Brain Fog
Studies also show that huperzine A can help with brain fog or mental fatigue.
One study in fact connected the folk herbalism use of clubmoss for chronic fatigue issues to its huperzine A content .
What’s more, brain fog isn’t an issue that just happens on its own. It can be a frustrating consequence of other health problems such as autoimmune disorders, digestive dysfunction, certain nervous conditions, or adrenal fatigue.
Huperzine A Could Protect Your Liver
Huperzine A isn’t just a nootropic, it has some other far-reaching benefits up its sleeve.
Many years ago and in the here and now, Huperzine A in Chinese medicine has been used for liver problems.
A study in 2013 showed that its AChE inhibiting benefits apparently reduce inflammation in the liver, thereby enhancing its health and function .
May Help With Addiction
There is one study, although results are very preliminary that shows Hup A may be able to slow or alter the immediate response to addiction, showing promise for the further development and exploration in the alkaloid for addiction treatment and management .
It’s untested for now, but huperzine A may provide support for those or trying to quit smoking or drinking, or even heavy drugs however more studies are needed.
Huperzine A is a great nootropic and natural at that, but it does have its own side effects you must be aware of. They include:
- Rashes and or hives as part of an allergic reaction
- hypertension (high blood pressure)
Huperzine-A can be toxic if used in larger than recommended doses. Or if you already have too much acetylcholine(ACh) in your system. Remember, Hup-A boosts levels of ACh.
Symptoms of acute toxicity are similar to those of other cholinergic inhibitors. And can include muscle tremors, drooling, tears, bronchial mucus and incontinence.
Do not use Huperzine-A if you’re dealing with epilepsy. And if you have heart disease, use Hup-a with caution. It can slow the heart rate.
Huperzine A may interact poorly with anticholinergic medications such as Atropine and Scopolamine; it may also interact with antihistamines and antidepressant medications. Those who are taking these medicines or who have heart disease, hypertension, or are taking anticholinergic medications for Alzheimer’s or glaucoma should discuss huperzine A with their doctor before taking it.
As is fairly normal for supplements, there are no medically recognized guidelines for Huperzine A dosage, but from manufacturers guidelines, a dosage of 50–200 mg twice daily for the treatment of Alzheimer’s disease, and 100 mg twice daily to improve memory in adolescents with or without food at any time of day.
Due to its long half-life of over 10 hours, cycling may be useful. A cycle of 2–4 weeks of supplementation followed by a break from supplementation is typical.
Unfortunately, Huperzine A has been an underdog or underrated nootropic, but shouldn’t be. It has its own powerful benefits to us as a memory enhancer, neuroprotectant, and reliever of symptoms of depression and helps treat neurodegenerative diseases such as Alzheimer’s. This is impressive on its own. Being what it is, it is a great nootropic to combine (stack) with other nootropics. It is safe and well tolerated when taken in moderation.
In fact, Huperzine A often has its effects elevated when used as a stack with other nootropics. If you take it with a choline source, such as Alpha GPC, you can experience a far greater improvement in memory and mental function.
Stacking Huperzine A with a choline source and a racetam, such as piracetam or aniracetam, can provide immense benefits. The added choline, along with Huperzine A’s effects, will combine very well with the racetam and you will probably notice a sense of mental clarity much stronger than that provided by the use of any individual nootropic.
Where to Buy Huperzine A
Huperzine A is a relatively safe nootropic, but a rare one. You may not find huperzine A for sale at your local health food store and it is best to search online for the natural supplement. A good place to start is the NootropicsDepot by clicking here or on the bottle to the right.